logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12017031 B1

PDFFull Text
Date of Patent:
Jun. 25, 2024

Filed:

Oct. 19, 2021

Nanopatterned medical device with enhanced cellular interaction

Applicant:

Sorrento Therapeutics, Inc., San Diego, CA (US);

Inventor:

Russell Frederick Ross, Jacksonville Beach, FL (US);

Assignee:

SORRENTO THERAPEUTICS, INC., San Diego, CA (US);

Attorney:

BAKER BOTTS L.L.P.

Primary Examiner:

Nathan R Price

Assistant Examiner:

Anh Bui

Int. Cl.
CPC ...
A61M 37/00 (2006.01); A61B 17/20 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 38/17 (2006.01); A61K 38/19 (2006.01); B29C 59/00 (2006.01); B29C 59/02 (2006.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
A61M 37/0015 (2013.01); A61B 17/205 (2013.01); A61K 9/0021 (2013.01); A61K 9/7023 (2013.01); A61K 38/1793 (2013.01); A61K 38/191 (2013.01); B29C 59/002 (2013.01); B29C 59/026 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/003 (2013.01); A61M 2037/0038 (2013.01); A61M 2037/0053 (2013.01); A61M 2037/0061 (2013.01); B29C 2059/023 (2013.01); B29K 2995/0056 (2013.01); B29L 2031/7544 (2013.01); B29L 2031/756 (2013.01); Y10T 156/10 (2015.01); Y10T 156/1039 (2015.01); Y10T 156/1057 (2015.01);
Abstract

A medical device for delivering a drug compound through a stratum corneum includes a support having an aperture, an array of microneedles extending outwardly from the support, a plurality of nanostructures associated with each microneedle, and a reservoir wherein the drug compound is retained. At least one microneedle contains a shaft extending from the support. The shaft includes a tip configured to penetrate the stratum corneum. The shaft defines a channel extending from the support to the tip. The channel is in at least partial alignment with the aperture. At least some of the microneedles of the array of microneedles each have a cross-sectional dimension of from about 1 micrometer to about 1 millimeter. At least some of the nanostructures have a cross-sectional dimension less than about 500 nanometers and greater than about 5 nanometers and an aspect ratio of from about 0.2 to about 5.

Find Patent Forward Citations

Loading…