The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Nov. 15, 2022
Applicants:
Crispr Therapeutics Ag, Zug, CH;
Bayer Healthcare Llc, Whippany, NJ (US);
Inventor:
Alan Richard Brooks, Cambridge, MA (US);
Assignees:
CRISPR THERAPEUTICS AG, Zug, CH;
BAYER HEALTHCARE LLC, Whippany, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); A61K 48/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61K 48/0066 (2013.01); A61K 48/0075 (2013.01); C12N 15/113 (2013.01); C12N 2310/141 (2013.01);
Abstract
Provided herein, in some embodiments, are materials and methods for treating hemophilia A in a subject ex vivo or in vivo. Also provided herein, in some embodiments, are materials and methods for knocking in a coding sequence encoding a synthetic FVIII having a B domain substitute into a genome.