The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Jan. 08, 2019
Applicant:

Seasun Therapeutics, Inc., Daejeon, KR;

Inventors:

Hye Joo Kim, Daejeon, KR;

Ji-Yeon Yu, Chungcheongbuk-do, KR;

Dong In Lee, Daejeon, KR;

Yusun Kang, Daejeon, KR;

Hee Kyung Park, Daejeon, KR;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 9/00 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); A61P 17/00 (2006.01); A61P 17/02 (2006.01); A61P 17/06 (2006.01); A61P 35/04 (2006.01); C12N 15/113 (2010.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6455 (2017.08); A61K 9/0014 (2013.01); A61K 47/549 (2017.08); A61P 17/00 (2018.01); A61P 17/02 (2018.01); A61P 17/06 (2018.01); A61P 35/04 (2018.01); C12N 15/113 (2013.01); C12N 15/1138 (2013.01); A61K 48/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/3519 (2013.01);
Abstract

A skin-penetrating carrier containing a nucleic acid complex having a novel structure which introduces a bioactive nucleic acid into cells. Composition for diagnosing, preventing or treating disease and to a skin-penetrating carrier containing a nucleic acid complex in which a bioactive nucleic acid and a carrier peptide nucleic acid are complementarily bound to each other, and having skin permeability and skin retention ability. Skin-penetrating carrier containing nucleic acid complex having structure of Structural Formula (1) has both a skin penetration function of effectively delivering a large-molecular-weight drug and in vivo effectiveness. Carrier enables bioactive nucleic acids or various compounds to pass through the epidermis and dermis of the skin, thus enables external treatment by application to the skin surface.


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