The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Apr. 04, 2018
Applicant:
Loma Linda University, Loma Linda, CA (US);
Inventors:
Kimberly J. Payne, Loma Linda, CA (US);
Olivia L. Francis-Boyle, Loma Linda, CA (US);
Assignee:
LOMA LINDA UNIVERSITY, Loma Linda, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 38/19 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); G01N 33/574 (2006.01); A61K 38/18 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2046 (2013.01); A61K 38/19 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); G01N 33/57426 (2013.01); G01N 33/57492 (2013.01); A61K 38/1808 (2013.01); A61K 45/06 (2013.01); G01N 33/57411 (2013.01); G01N 33/57423 (2013.01); G01N 33/57449 (2013.01);
Abstract
In one aspect, methods of treating a subject having a cancer that expresses a cytokine receptor are provided. In some embodiments, the method comprises administering to the subject a biologic agent in an amount sufficient to induce loss of cytokine receptor signaling through increased expression of a Suppressor of Cytokine Signaling genes and/or loss of one or more cytokine receptor components from the cancer cell surface. In some embodiments, the biologic agent is a cytokine or cytokine mimetic.