System and method of tractography labeling in the presence of brain lesion

Abstract

A system and methods for labeling tractography, having a tract segmentation and a tract labeling atlas, in a presence of a lesion in a brain, involving: a graphical user interface (GUI) comprising a tool configured to facilitate adjusting a displacement for intraoperatively reperforming the tract segmentation in approximately real time, modeling deformation of the tract labeling atlas by facilitating modeling a force exerted by the lesion on the brain, and defining parameters of a size, a shape, and a level of the displacement condition; and a processor in communication with the GUI and configured to: determine whether an infiltration condition and a displacement condition appears in the tractography; if the infiltration condition and the displacement condition is determined to appear in the tractography, estimate the infiltration condition and the displacement condition; if the displacement condition is determined to appear in the tractography, instruct the GUI to render the tool and model the force exerted by the lesion on the brain by using the parameters, whereby a new tract segmentation and a new tract labeling atlas are provided; and if the displacement condition is determined to be absent from the tractography, refrain from modeling the force, a presence of only the infiltration condition being assumed.