The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Jul. 09, 2021
Applicants:

Rhode Island Hospital, Providence, RI (US);

Brown University, Providence, RI (US);

Inventors:

William Keun Chan Park, Westerly, RI (US);

Damian E. Dupuy, Centerville, MA (US);

Assignees:

Rhode Island Hospital, Providence, RI (US);

Brown University, Providence, RI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 18/18 (2006.01); A61B 18/14 (2006.01); A61K 45/06 (2006.01); A61B 18/00 (2006.01);
U.S. Cl.
CPC ...
A61B 18/1815 (2013.01); A61B 18/14 (2013.01); A61K 45/06 (2013.01); A61B 2018/00095 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00595 (2013.01); A61B 2018/00982 (2013.01);
Abstract

A thermal accelerant is delivered to a tissue site and localized to modulate the shape, extent or other characteristic of RF or microwave-induced hyperthermic tissue ablation. The accelerant may be provided via an image-guided hand piece or via a lumen added to a microwave antenna, and promotes faster heating, more complete ablation and/or a more extensive treatment region to reduce recurrence of treated cancers, overcoming natural limitations, variations in tissue response and drop-off or thermal loss away from the antenna. The accelerant is delivered as a viscous but heat sensitive fluid, and is fixed in place to provide regions of preferential absorption or heating. Shorter exposure times to heat the far field may allow survival of vulnerable tissue such as vessels, and multiple antennae may be used for effective treatment of irregular or large tumors.


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