The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Dec. 08, 2021
Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Jeffrey Charles Johnson, West Point, PA (US);

Anthony Flammino, Whitehouse Station, NJ (US);

Mark Anton Petrich, West Point, PA (US);

Scott McFeaters, West Point, PA (US);

John H. Roosa, Jr., Rahway, NJ (US);

Robert Ian Alpern, Lansdale, PA (US);

Joseph W. Locurcio, Whitehouse Station, NJ (US);

Matthew H. Flamm, West Point, PA (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 1/02 (2006.01); A61J 1/00 (2023.01); B65D 81/00 (2006.01); B65D 81/02 (2006.01); B65D 81/18 (2006.01); B65D 81/24 (2006.01); F25D 11/00 (2006.01);
U.S. Cl.
CPC ...
A01N 1/0268 (2013.01); A01N 1/0263 (2013.01); A01N 1/0273 (2013.01); A61J 1/00 (2013.01); B65D 81/00 (2013.01); B65D 81/027 (2013.01); B65D 81/18 (2013.01); B65D 81/24 (2013.01); F25D 11/003 (2013.01);
Abstract

Container system and method for freezing (and subsequently thawing) a liquid such as a drug substance, such that all containers in a set have a uniform width, hence uniform freeze-path length, in the widthwise direction and perpendicular to major walls of the containers, irrespective of the particular length, height, and volumetric capacity of the various containers in the set. This leads to uniform freezing performance and thereby reduces cryoconcentration. The system also eliminates or reduces ice-bridging, and the potential for containers rupturing during freezing and thawing operations.


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