The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2024

Filed:

May. 04, 2023
Applicant:

Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, CN;

Inventors:

Han Xia, Wuhan, CN;

Zhiming Yuan, Wuhan, CN;

Nanjie Ren, Wuhan, CN;

Fei Wang, Wuhan, CN;

Guilin Zhang, Wuhan, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 7/00 (2006.01); C12N 7/01 (2006.01); G01N 33/50 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5091 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 2760/12021 (2013.01); C12N 2760/12043 (2013.01); C12N 2760/12052 (2013.01); G01N 2333/175 (2013.01);
Abstract

The present application discloses a nucleic acid composition for expressing recombinant EBIV-related genes and proteins and the use thereof. The nucleic acid composition includes a nucleic acid molecule having sequences shown in SEQ ID NO. 14, 15, 16, and 17. In the present application, a recombinant EBIV is also constructed with this nucleic acid composition. The virus not only has broad-spectrum infectivity to mammalian and mosquito cells, can be stably passaged, but also has green fluorescence, which can provide a research foundation for in vitro and in vivo virus tracing, virus detection, antiviral drugs, vaccine screening, with significant application prospects.


Find Patent Forward Citations

Loading…