The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2024
Filed:
Jan. 08, 2019
Diasys Diagnostic Systems Gmbh, Holzheim, DE;
Matthias Grimmler, Elz, DE;
Detlef Thônges, Limburg, DE;
Pia Schu, Schmelz, DE;
Carolin Menzenbach, Pleckhausen, DE;
Laura Kreckel, Elz, DE;
DiaSys Diagnostic Systems GmbH, Holzheim, DE;
Abstract
A method for quantitatively determining the amount of acetaminophen in a sample with greater precision, greater sensitivity and fewer interactions and fewer spectral and chemical interferences with other compounds contained in the sample. The method includes acetaminophen being hydrolyzed and the resulting p-aminophenol being reacted with a compound of general formula (III): in the presence of an oxidant to form a compound of general formula (IV): wherein R1 and R2, independently of one another, are selected from H, —CH, and —OCH, R3 is —CHand R4 is a Calkyl moiety with a terminal sulfonate group, with the proviso that at least one of R1 and R2 is —OCHand/or R4 additionally has at least one OH substituent, and then the amount of the compound of general formula (IV) in the reaction mixture being photometrically determined.