The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2024

Filed:

Apr. 10, 2019
Applicants:

Amgen Inc., Thousand Oaks, CA (US);

Kite Pharma, Inc., Santa Monica, CA (US);

Inventors:

Michael John Giffin, Newbury Park, CA (US);

Melissa Thomas, Palo Alto, CA (US);

Christopher Murawsky, Roberts Creek, CA;

Ryan B. Case, Alameda, CA (US);

Lawren Wu, Foster City, CA (US);

Jed J. Wiltzius, Winchester, MA (US);

Ruben Alvarez Rodriguez, Los Angeles, CA (US);

Jun Feng, Los Angeles, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61P 35/00 (2018.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C12N 15/86 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C12N 2740/15041 (2013.01);
Abstract

Antigen binding molecules, chimeric receptors, and engineered immune cells to DLL3 are disclosed in accordance with the invention. The invention further relates to vectors, compositions, and methods of treatment and/or detection using the DLL3 antigen binding molecules and engineered immune cells.


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