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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12012411 B1

PDFFull Text
Date of Patent:
Jun. 18, 2024

Filed:

Nov. 30, 2021

Viral replication inhibitors

Applicant:

Katholieke Universiteit Leuven, Leuven, BE;

Inventors:

Dorothée Bardiot, Leuven, BE;

Gunter Carlens, Leuven, BE;

Kai Dallmeier, Leuven, BE;

Suzanne Kaptein, Leuven, BE;

Michael McNaughton, Leuven, BE;

Arnaud Marchand, Leuven, BE;

Johan Neyts, Leuven, BE;

Wim Smets, Leuven, BE;

Mohamed Koukni, Leuven, BE;

Assignee:

Katholieke Universiteit Leuven, Leuven, BE;

Attorneys:

Burns & Levinson, LLP

Shawn P. Foley

Chris Lorenc

Primary Examiner:

Shawquia Jackson

Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 209/14 (2006.01); C07D 401/06 (2006.01); C07D 401/08 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 403/08 (2006.01); C07D 403/10 (2006.01); C07D 403/12 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 409/06 (2006.01); C07D 409/08 (2006.01); C07D 409/12 (2006.01); C07D 413/06 (2006.01); C07D 413/08 (2006.01); C07D 413/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 209/14 (2013.01); C07D 401/06 (2013.01); C07D 401/08 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 403/08 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 409/06 (2013.01); C07D 409/08 (2013.01); C07D 409/12 (2013.01); C07D 413/06 (2013.01); C07D 413/08 (2013.01); C07D 413/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.

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