The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2024

Filed:

Sep. 22, 2022
Applicant:

Therapeutic Solutions International, Inc., Oceanside, CA (US);

Inventors:

Thomas E. Ichim, Oceanside, CA (US);

Famela Ramos, Oceanside, CA (US);

James Veltmeyer, Oceanside, CA (US);

Timothy G. Dixon, Oceanside, CA (US);

Feng Lin, Oceanside, CA (US);

Kalina O'Connor, Oceanside, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61K 35/28 (2015.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 35/28 (2013.01); A61P 11/00 (2018.01);
Abstract

Disclosed are novel means of enhancing mesenchymal stem cell regenerative activities including, intra alia, production from pulmonary leakage and suppression of scar tissue formation by co-administration with T regulatory cells. In some embodiments the invention provides an interaction between T regulatory cells and mesenchymal stem cells in which T regulatory cells stimulate upregulation of mesenchymal stem cell activity in a GITR dependent manner.


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