The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2024
Filed:
Feb. 20, 2019
Universite DE Montreal, Montréal, CA;
Guy Sauvageau, Montréal, CA;
Sandra Cohen, Montréal, CA;
Jean Roy, Ville Mont-Royal, CA;
Silvy Lachance, Westmount, CA;
Jean-Sébastien Delisle, Saint-Lambert, CA;
Jalila Chagraoui, Montreal, CA;
UNIVERSITE DE MONTREAL, Montréal, CA;
Abstract
It is provided a method of expanding dendritic (DC) cells and/or natural killer (NK) cells in vivo in a patient comprising the steps of producing a graft of stem and progenitor cells cultured with UM171 or analogues therefrom and expanded before being administered to the patient. The expansion or increase in dendritic (DC) cells and/or natural killer (NK) cells population in the patient results in an increase immune response reducing transplant related mortality (TRM), severe graft-versus-host disease (GVHD), relapse, and/or severe viral infections.