The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2024
Filed:
Feb. 21, 2023
Applicant:
Board of Regents of the University of Nebraska, Lincoln, NE (US);
Inventors:
Dong Wang, Omaha, NE (US);
Fang Yuan, Wheaton, MD (US);
Zhenshan Jia, Omaha, NE (US);
Xiaobei Wang, Omaha, NE (US);
Assignee:
Board of Regents of the University of Nebraska, Lincoln, NE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/57 (2006.01); A61K 9/107 (2006.01); A61K 47/10 (2017.01); A61K 47/34 (2017.01); C07J 41/00 (2006.01); C07J 51/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/57 (2013.01); A61K 9/1075 (2013.01); A61K 47/10 (2013.01); A61K 47/34 (2013.01); C07J 41/0005 (2013.01); C07J 41/0016 (2013.01); C07J 51/00 (2013.01);
Abstract
Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.