The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2024
Filed:
May. 27, 2022
Applicant:
Mcmaster University, Hamilton, CA;
Inventors:
Eric Brown, Oakville, CA;
Omar M Elhalfawy, Regina, CA;
Nick Jentsch, Fenton, MO (US);
Xiong Zhang, Tianjin, CN;
Jakob Magolan, Grimsby, CA;
Assignee:
McMaster University, Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/055 (2006.01); A61K 31/05 (2006.01); A61K 31/11 (2006.01); A61K 31/121 (2006.01); A61K 31/341 (2006.01); A61K 31/381 (2006.01); A61K 31/42 (2006.01); A61K 31/4418 (2006.01); A61K 31/47 (2006.01); A61K 31/505 (2006.01); A61K 38/12 (2006.01); A61P 31/04 (2006.01); C07C 39/19 (2006.01); C07C 43/275 (2006.01); C07C 49/78 (2006.01); C07C 205/18 (2006.01); C07D 213/30 (2006.01); C07D 215/14 (2006.01); C07D 239/26 (2006.01); C07D 239/42 (2006.01); C07D 261/08 (2006.01); C07D 307/48 (2006.01); C07D 333/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/055 (2013.01); A61K 31/05 (2013.01); A61K 31/11 (2013.01); A61K 31/121 (2013.01); A61K 31/341 (2013.01); A61K 31/381 (2013.01); A61K 31/42 (2013.01); A61K 31/4418 (2013.01); A61K 31/47 (2013.01); A61K 31/505 (2013.01); A61K 38/12 (2013.01); A61P 31/04 (2018.01); C07C 39/19 (2013.01); C07C 43/275 (2013.01); C07C 49/78 (2013.01); C07C 205/18 (2013.01); C07D 213/30 (2013.01); C07D 215/14 (2013.01); C07D 239/26 (2013.01); C07D 239/42 (2013.01); C07D 261/08 (2013.01); C07D 307/48 (2013.01); C07D 333/38 (2013.01);
Abstract
Provided herein are novel synthetic compounds having the structure of formula (1), wherein X is a substituted or unsubstituted aromatic or heteroaromatic mono- or polycyclic ring system; and Y is substituted or unsubstituted C-Calkyl or alkenyl group, or a pharmaceutically acceptable salt thereof. Also provided are pharmaceutical compositions. The compounds and pharmaceutical compositions are useful for inhibiting growth of a bacterium.