The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2024

Filed:

May. 29, 2020
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Anant Madabhushi, Shaker Heights, OH (US);

Hersh Bhargava, San Francisco, CA (US);

Patrick Leo, Honeoye Falls, NY (US);

Priti Lal, Ellicott City, MD (US);

Assignee:

Case Western Reserve University, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16H 50/30 (2018.01); G06N 7/01 (2023.01); G06N 20/00 (2019.01); G06T 7/00 (2017.01); G06T 7/11 (2017.01); G06V 10/778 (2022.01); G16H 30/40 (2018.01);
U.S. Cl.
CPC ...
G06T 7/0012 (2013.01); G06N 7/01 (2023.01); G06N 20/00 (2019.01); G06T 7/11 (2017.01); G06V 10/7796 (2022.01); G16H 30/40 (2018.01); G16H 50/30 (2018.01); G06T 2207/20076 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/30081 (2013.01);
Abstract

Embodiments discussed herein facilitate determination of one of a probability of prostate cancer recurrence-free survival or a risk factor associated with prostate cancer based on intra-tumor stromal morphology. Example embodiments can perform operations comprising: accessing a digitized histological image of a prostate of a patient, wherein the histological image comprises a region of interest associated with prostate cancer; identifying nuclei of intra-tumoral stromal cells within the region of interest; extracting, for the region of interest of the digitized histological image, one or more features describing the structure of the intra-tumoral stromal cells; and generating, via a model based at least on the one or more features, one of a probability of prostate cancer recurrence-free survival or a risk score associated with prostate cancer for the patient based at least on the extracted one or more features.


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