The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2024
Filed:
Dec. 21, 2018
Fundació Privada Institut D'investigació Oncològica DE Vall Hebron, Barcelona, ES;
Astrazeneca Uk Limited, Cambridge, GB;
Xentech Sas, Evry, FR;
Violeta Serra Elizalde, Barcelona, ES;
Judith Balmaña Gelpi, Barcelona, ES;
Cristina Cruz Zambrano, Barcelona, ES;
Alba Llop Guevara, Barcelona, ES;
Marta Castroviejo Bermejo, Logroño, ES;
Mark J. O'Connor, Little Chesterford, GB;
Gemma Nicole Jones, Little Chesterford, GB;
FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCÒLOGICA DE VALL HEBRON, Barcelona, ES;
ASTRAZENECA UK LIMITED, Cambridge, GB;
XENTECH SAS, Evry, FR;
Abstract
The invention provides a method allowing to determine whether a subject diagnosed with cancer is sensitive or resistant to an anti-cancer treatment, based on the level of cells with RAD51 foci in a sample containing tumor cells isolated from said subject, wherein the subject has not received at 24 hours prior to the isolation of the sample, a chemotherapy selected from the group consisting of AC, FEC, ECF and navelbine/epirubicin, and wherein the sample has not been treated with a method that induces DNA damage before determining the level of cells with RAD51 foci.