The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2024

Filed:

Dec. 17, 2021
Applicant:

Debut Biotechnology, Inc., San Diego, CA (US);

Inventors:

Joshua Britton, San Diego, CA (US);

Nicholas Brideau, San Diego, CA (US);

Assignee:

DEBUT BIOTECHNOLOGY, INC., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 9/00 (2006.01); B01L 3/00 (2006.01); C12P 7/42 (2006.01);
U.S. Cl.
CPC ...
C12P 9/00 (2013.01); B01L 3/00 (2013.01); C12P 7/42 (2013.01); B01L 2200/028 (2013.01); B01L 2200/0631 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/146 (2013.01); B01L 2200/147 (2013.01); B01L 2300/048 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/163 (2013.01); B01L 2300/1894 (2013.01);
Abstract

Geranyl pyrophosphate (GPP) is a key intermediate molecule in the bioproduction of thousands of natural products. Currently, natural products are either cultivated from plants, synthesized via complex chemical synthesis strategies, or through cell-based factories also known as biofoundries. However, in order to replicate the process in a cell free environment, numerous enzymes and cofactors must be utilized making this approach costly and unviable. In order to make this process viable, a new approach was needed that uses fewer enzymes and co-factors. As described herein, the present invention demonstrates that it is possible to create GPP from glycerol through a short and concise biosynthetic pathway outside of the cell.


Find Patent Forward Citations

Loading…