The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2024
Filed:
Jan. 19, 2018
Applicant:
Kyoto University, Kyoto, JP;
Inventors:
Shin Kaneko, Kyoto, JP;
Yohei Kawai, Kyoto, JP;
Assignee:
KYOTO UNIVERSITY, Kyoto, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 35/17 (2015.01); C12N 5/00 (2006.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0638 (2013.01); A61K 35/17 (2013.01); C12N 5/0018 (2013.01); C12N 5/0696 (2013.01); C12N 2500/38 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/2312 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/2318 (2013.01); C12N 2501/2321 (2013.01); C12N 2501/26 (2013.01); C12N 2501/42 (2013.01); C12N 2501/50 (2013.01); C12N 2501/998 (2013.01); C12N 2506/45 (2013.01); C12N 2533/52 (2013.01);
Abstract
A method efficiently produces cytotoxic T lymphocytes having intrinsic properties of lymphocytes of the acquired immune system suitable for cellular immunotherapy. The method includes culturing CD4/CD8 double-positive T cells in a medium containing IL-7 and a T-cell receptor activator, to induce CD8αβcytotoxic T lymphocytes.