The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2024
Filed:
Apr. 14, 2020
The Medical College of Wisconsin, Inc., Milwaukee, WI (US);
University of Virginia Patent Foundation, Charlottesville, VA (US);
Kaothara Oluwakemi Adeyanju, Milwaukee, WI (US);
Jeffrey A. Medin, Shorewood, WI (US);
Robert Blake Hill, Milwaukee, WI (US);
Lawrence G. Lum, Charlottesvilla, VA (US);
The Medical College of Wisconsin, Inc., Milwaukee, WI (US);
University of Virginia Patent Foundation, Charlottesville, VA (US);
Abstract
The present disclosure provides soluble truncated mutant programmed death-ligand 1 (PD-L1) peptides. Polynucleotides and vectors encoding the soluble truncated mutant PD-L1 peptides are also provided. Further, methods of using the soluble truncated mutant peptides to promote differentiation of CD4+ effector T (Th1) cells into Foxp3+ regulatory T (Treg) cells are provided.