The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2024

Filed:

Nov. 18, 2015
Applicant:

Emory University, Atlanta, GA (US);

Inventors:

Stephen F. Traynelis, Decatur, GA (US);

Lanny S. Liebeskind, Atlanta, GA (US);

Dennis C. Liotta, Atlanta, GA (US);

Ethel C. Garnier-Amblard, Tucker, GA (US);

PavanKumar Reddy Gangireddy, Atlanta, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61P 25/16 (2018.01); A61P 25/18 (2018.01); A61P 25/22 (2018.01); A61P 25/28 (2018.01);
Abstract

The disclosure relates thieno[2,3-d]pyrimidin-4-one derivatives as modulators of NMDA receptors and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for managing conditions related to cognition, typically prevention or treatment of neurological conditions related to the NMDA receptor.


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