The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2024

Filed:

Jul. 01, 2022
Applicant:

Sericultural&agri-food Research Institute Guangdong Academy of Agricultural Sciences, Guangzhou, CN;

Inventors:

Mingwei Zhang, Guangzhou, CN;

Yuanyuan Deng, Guangzhou, CN;

Guang Liu, Guangzhou, CN;

Yan Zhang, Guangzhou, CN;

Zhencheng Wei, Guangzhou, CN;

Pengfei Zhou, Guangzhou, CN;

Ping Li, Guangzhou, CN;

Zhihao Zhao, Guangzhou, CN;

Xuchao Jia, Guangzhou, CN;

Xiaojun Tang, Guangzhou, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 407/12 (2006.01); A61K 36/42 (2006.01);
U.S. Cl.
CPC ...
C07D 407/12 (2013.01); A61K 36/42 (2013.01);
Abstract

The present invention relates to the technical field of natural medicines, and in particular to a triterpenoid compound with an effect of improving glucose and lipid metabolism disorders, and preparation and application thereof. A novel triterpenoid compound was obtained by separation fromL. for the first time in the present invention. Studies on a mouse primary hepatocyte model and a 3T3-L1 preadipocyte model show that the novel triterpenoid compound in the present invention has activity of regulating glucose and lipid metabolism, and after combination with known triterpenoid compound Momordicoside G, the activity of regulating glucose and lipid metabolism is significantly higher than that of a single compound at the same dose, indicating that the novel triterpenoid compound and a complex thereof in the present invention can be used to improve glucose and lipid metabolism disorders and provide a new way for diabetes treatment.


Find Patent Forward Citations

Loading…