The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2024
Filed:
Jul. 03, 2023
Applicant:
Newamsterdam Pharma B.v., Naarden, NL;
Inventors:
Sheng Cui, Lexington, MA (US);
Andreas René Rötheli, Wellesley, MA (US);
Christopher J. Borths, Sherborn, MS (US);
Muneki Kishida, Osaka, JP;
Assignee:
NewAmsterdam Pharma B.V., Naarden, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 31/33 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/33 (2013.01); A61P 9/00 (2018.01); C07B 2200/13 (2013.01);
Abstract
Provided herein is a method for the manufacture of a compound of obicetrapib and salts thereof, such as calcium salts thereof. Also provided herein is amorphous obicetrapib hemicalcium. New intermediates for use in the synthesis of obicetrapib, and salts thereof are also provided, including obicetrapib HCl and a mesylate salt for the use in the synthesis of obicetrapib and amorphous obicetrapib hemicalcium.