The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2024
Filed:
Aug. 12, 2021
Applicant:
Minerva Neurosciences, Inc., Waltham, MA (US);
Inventors:
Remy Luthringer, Geneva, CH;
Nadine Noel, Gildwiller, FR;
Florent Schmitt, Uttenheim, FR;
Sandra Werner, Ostwald, FR;
Hans Maag, Oberammergau, DE;
Jay Saoud, Groton, MA (US);
Assignee:
Minerva Neurosciences, Inc., Burlington, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 217/06 (2006.01); C07D 217/08 (2006.01); C07D 223/16 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/10 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 417/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); C07D 217/06 (2013.01); C07D 217/08 (2013.01); C07D 223/16 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 417/06 (2013.01);
Abstract
The present disclosure relates to compounds of Formula (I): and their prodrugs, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods of their preparation. The compounds disclosed herein are useful for modulating Sigma receptors and have antiviral activity, and may also be useful in the treatment and/or prevention of pain disorders, neurological disorders (e.g., Parkinson's disease and Alzheimer's disease), and cancer.