The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2024

Filed:

Dec. 28, 2018
Applicant:

Medica Corporation, Bedford, MA (US);

Inventors:

Ronald Jones, Newton, NH (US);

Adrian Gropper, Watertown, MA (US);

Robert Hagopian, Belmont, MA (US);

Charles Rogers, Halifax, MA (US);

Thomas Vitella, Sandown, NH (US);

Tyler Cote, Chelmsford, MA (US);

Donald Barry, Groton, MA (US);

Dirk Osterloh, Arlington, MA (US);

Chen Yi, Boxborough, MA (US);

Assignee:

Medica Corporation, Bedford, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 15/00 (2006.01); G01N 15/02 (2006.01); G01N 15/14 (2006.01); G01N 33/569 (2006.01); G01N 15/0227 (2024.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); G01N 15/1475 (2013.01); G01N 15/1484 (2013.01); G01N 33/56966 (2013.01); B01L 2200/0605 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0883 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0622 (2013.01); B01L 2400/0644 (2013.01); G01N 2015/0073 (2013.01); G01N 2015/008 (2013.01); G01N 2015/0084 (2013.01); G01N 15/0227 (2013.01); G01N 2015/1493 (2013.01);
Abstract

This disclosure describes single-use test cartridges, cell analyzer apparatus, and methods for automatically performing microscopic cell analysis tasks, such as counting and analyzing blood cells in biological samples. A small measured quantity of a biological sample, such as whole blood, is placed in a mixing bowl on the disposable test cartridge after being inserted into the cell analyzer. The analyzer also deposits a known amount of diluent/stain in the mixing bowl and mixes it with the blood. The analyzer takes a measured amount of the mixture and dispenses in a sample cup on the cartridge in fluid communication with an imaging chamber. The geometry of the imaging chamber is chosen to maintain the uniformity of the mixture, and to prevent cells from crowding or clumping as it is transferred into the imaging chamber by the analyzer. Images of all of the cellular components within the imaging chamber are counted and analyzed to obtain a complete blood count.


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