The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2024

Filed:

Aug. 10, 2022
Applicants:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Justin Williams, Madison, WI (US);

Kip Ludwig, Rochester, MN (US);

Erika Ross, San Mateo, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61N 1/05 (2006.01); A61N 1/04 (2006.01); A61N 1/36 (2006.01); A61N 1/375 (2006.01);
U.S. Cl.
CPC ...
A61N 1/056 (2013.01); A61N 1/0456 (2013.01); A61N 1/0476 (2013.01); A61N 1/0484 (2013.01); A61N 1/0492 (2013.01); A61N 1/0536 (2013.01); A61N 1/0551 (2013.01); A61N 1/36025 (2013.01); A61N 1/36034 (2017.08); A61N 1/36053 (2013.01); A61N 1/36067 (2013.01); A61N 1/36082 (2013.01); A61N 1/36103 (2013.01); A61N 1/36132 (2013.01); A61N 1/36146 (2013.01); A61N 1/36175 (2013.01); A61N 1/37516 (2017.08);
Abstract

The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopathy are provided. For example, the present invention provides materials and methods for modulating glymphatic clearance (e.g., enhancing glymphatic clearance) of pathogenic proteins.


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