The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2024

Filed:

Jan. 16, 2019
Applicant:

Vertex Pharmaceuticals Incorporated, Boston, MA (US);

Inventors:

John Patrick Maxwell, Hingham, MA (US);

Katrina Lee Jackson, Weston, MA (US);

Qing Tang, Boxborough, MA (US);

Mark A. Morris, Somerville, MA (US);

Steven M. Ronkin, Watertown, MA (US);

Jinwang Xu, Framingham, MA (US);

Kevin M. Cottrell, Cambridge, MA (US);

Paul S. Charifson, Framingham, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/74 (2006.01); A61K 48/00 (2006.01); C07D 239/88 (2006.01); C07D 239/94 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 417/12 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0066 (2013.01); A61K 48/0075 (2013.01); C07D 239/74 (2013.01); C07D 239/88 (2013.01); C07D 239/94 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 417/12 (2013.01); C07D 491/048 (2013.01);
Abstract

The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various diseases, conditions, or disorders.


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