The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2024
Filed:
May. 07, 2019
Applicant:
Regulus Therapeutics Inc., San Diego, CA (US);
Inventors:
Charles R. Allerson, San Diego, CA (US);
Steven S. Neben, Del Mar, CA (US);
Timothy Wright, San Diego, CA (US);
Assignee:
Regulus Therapeutics Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61K 31/439 (2006.01); A61K 31/7072 (2006.01); A61K 31/7088 (2006.01); A61P 31/14 (2006.01);
U.S. Cl.
CPC ...
A61K 47/549 (2017.08); A61K 31/439 (2013.01); A61K 31/7072 (2013.01); A61K 31/7088 (2013.01); A61P 31/14 (2018.01);
Abstract
Described herein are compositions and methods for the inhibition of miR-122 activity. The compositions have certain nucleoside modifications that yield potent inhibitors of miR-122 activity and comprise moieties that facilitate delivery to the liver. The compositions may be administered to subjects infected with hepatitis C virus, as a treatment for hepatitis C virus and related conditions.