The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2024

Filed:

Oct. 26, 2020
Applicant:

Joslin Diabetes Center, Inc., Boston, MA (US);

Inventors:

Laurie J. Goodyear, Southborough, MA (US);

Kristin Stanford, Columbus, OH (US);

Assignee:

Joslin Diabetes Center, Inc., Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/201 (2006.01); A61P 3/04 (2006.01); A61P 21/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/201 (2013.01); A61P 3/04 (2018.01); A61P 21/06 (2018.01);
Abstract

The invention includes methods and compositions for treating a metabolic disorder, such as metabolic syndrome, hyperlipidemia and associated disorders, such as obesity and diabetes. The invention includes a method of treating a human subject comprising administering 12,13-dihydroxy-9Z-octadecenoic acid (12,13-diHOME) to the subject. The invention also includes methods and compositions for treating disorders and conditions that would benefit from skeletal muscle fatty acid uptake and oxidation, increased mitochondrial respiration in skeletal muscle and/or enhanced exercise capacity.


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