The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2024

Filed:

Jan. 16, 2018
Applicants:

Children's Medical Center Corporation, Boston, MA (US);

Ospedale San Raffaele S.r.l., Milan, IT;

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Fondazione Telethon, Rome, IT;

Inventors:

Alessandra Biffi, Boston, MA (US);

Eleonora Cavalca, Milan, IT;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); A61K 9/00 (2006.01); A61K 35/28 (2015.01); A61K 35/76 (2015.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61K 9/0019 (2013.01); A61K 9/0085 (2013.01); A61K 35/28 (2013.01); A61K 35/76 (2013.01); G01N 2333/825 (2013.01); G01N 2800/04 (2013.01); G01N 2800/50 (2013.01);
Abstract

The invention features compositions and methods for the treatment and prevention of peroxisomal diseases (e.g., neonatal adrenoleukodystrophy and Zellweger syndrome), including in a subject selected as having increased levels of metallothionein polypeptides. The invention also provides compositions and methods for identifying a subject having a peroxisomal disease involving detecting metallothionein polypeptides or polynucleotides.


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