The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2024
Filed:
Dec. 18, 2020
Applicant:
Becton, Dickinson and Company, Franklin Lakes, NJ (US);
Inventors:
Majid Mehrpouyan, Gilroy, CA (US);
Oleg Guryev, San Jose, CA (US);
Assignee:
BECTON, DICKINSON AND COMPANY, Franklin Lakes, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/58 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 33/586 (2013.01); G01N 21/6428 (2013.01); G01N 21/6486 (2013.01); G01N 33/582 (2013.01); G01N 2496/00 (2013.01);
Abstract
Methods of quantitating extra-cellular vesicle surface markers are provided. Aspects of the methods include comparing: a mean fluorescence intensity of a surface marker of interest (surface marker MFI) of a labeled extra-cellular vesicle (EV) sample with a calibration plot obtained from a liposome calibration composition to quantitate the surface marker on extra-cellular vesicles of the EV sample. Also provided are compositions that find use in practicing embodiments of the invention.