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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11999956 B1

PDFFull Text
Date of Patent:
Jun. 04, 2024

Filed:

Sep. 07, 2022

Targeted therapy composition and its use for suppressing breast cancer cell proliferation, migration or invasion

Applicant:

National Cheng Kung University, Tainan, TW;

Inventors:

Nan-Haw Chow, Tainan, TW;

Yi-Wen Wang, Tainan, TW;

Yih-Lin Tuan, Tainan, TW;

Yao-Lung Kuo, Tainan, TW;

Assignee:

NATIONAL CHENG KUNG UNIVERSITY, Tainan, TW;

Attorneys:

Locke Lord LLP

Tim Tingkang Xia, Esq.

Primary Examiner:

J E Angell

Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/155 (2006.01); A61K 31/713 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 31/155 (2013.01); A61K 31/713 (2013.01); A61P 35/00 (2018.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01);
Abstract

The present invention discloses a targeted therapy composition and a method for suppressing breast cancer cell proliferation, migration or invasion by administrating the targeted therapy composition to a subject in need thereof. The composition comprises a type 3 epithelial membrane proteins (EMP3) targeted inhibitor. The breast cancer cells are characterized by upregulation of EMP3, EGFR, HER2, HER3, HR, or downregulation of HER4 gene expression. EMP3-targeting oligonucleotide or nuclease is administrated upon the breast cancer cells so as to degrade EMP3-coding DNA or mRNA, and to suppress breast cancer cell proliferation, migration or invasion.

Find Patent Forward Citations

Chow, Nan-Haw. (2024). Targeted therapy composition and its use for suppressing breast cancer cell proliferation, migration or invasion (U.S. Patent No. 11999956). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11999956

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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