The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2024

Filed:

Apr. 21, 2021
Applicants:

Toolgen Incorporated, Seoul, KR;

Seoul National University R&db Foundation, Seoul, KR;

Seoul National University Hospital, Seoul, KR;

Inventors:

Jeong Hun Kim, Seoul, KR;

Sung Wook Park, Seoul, KR;

Seokjoong Kim, Seoul, KR;

Dong Woo Song, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); A61K 9/00 (2006.01); A61K 38/46 (2006.01); A61K 48/00 (2006.01); C07K 14/47 (2006.01); C07K 14/515 (2006.01); C07K 14/52 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); A61K 9/0048 (2013.01); A61K 38/465 (2013.01); A61K 48/00 (2013.01); A61K 48/005 (2013.01); C07K 14/4702 (2013.01); C07K 14/515 (2013.01); C07K 14/52 (2013.01); C12N 9/22 (2013.01); C12N 15/113 (2013.01); C12N 15/1136 (2013.01); C12N 15/86 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); C12N 2310/20 (2017.05); C12N 2750/14143 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present invention relates to an artificially manipulated neovascularization-associated factor for regulating neovascularization and a use thereof. More particularly, the present invention relates to a system for artificially regulating neovascularization, which includes an artificially manipulated neovascularization-associated factor for regulating neovascularization and/or a composition for artificially manipulating the neovascularization-associated factor. In a specific aspect, a neovascularization regulatory system including a neovascularization-associated factor such as artificially manipulated VEGFA, HIF1A, ANGPT2, EPAS1, or ANGPTL4 and/or an expression product thereof is provided.


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