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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11999802 B1

PDFFull Text
Date of Patent:
Jun. 04, 2024

Filed:

Oct. 18, 2018

Compositions and methods for selective protein degradation

Applicant:

Novartis Ag, Basel, CH;

Inventors:

James E. Bradner, Weston, MA (US);

Andrei Golosov, Cambridge, MA (US);

Carleton Proctor Goold, Brighton, MA (US);

Carla Patricia Pinto Guimaraes, Boston, MA (US);

Marc Horst Peter Hild, Wellesley, MA (US);

Gregory Motz, Quincy, MA (US);

Nathan Thomas Ross, Cambridge, MA (US);

Jonathan M. Solomon, Somerville, MA (US);

Rohan Eric John Beckwith, Maynard, MA (US);

Seth Carbonneau, Roxbury, MA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:

K&L Gates LLP

Primary Examiner:

Phuong Huynh

Int. Cl.
CPC ...
C07K 19/00 (2006.01); A61K 31/4545 (2006.01); A61K 31/46 (2006.01); A61K 35/12 (2015.01); C07D 209/48 (2006.01); C07D 213/81 (2006.01); C07D 401/14 (2006.01); C07D 451/02 (2006.01); C07K 14/435 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C12N 9/06 (2006.01); C12N 15/63 (2006.01); C12N 15/86 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 19/00 (2013.01); A61K 31/4545 (2013.01); A61K 31/46 (2013.01); A61K 35/12 (2013.01); C07D 209/48 (2013.01); C07D 213/81 (2013.01); C07D 401/14 (2013.01); C07D 451/02 (2013.01); C07K 14/435 (2013.01); C07K 14/705 (2013.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 14/70575 (2013.01); C07K 16/18 (2013.01); C07K 16/2803 (2013.01); C07K 16/2815 (2013.01); C07K 16/2863 (2013.01); C07K 16/2875 (2013.01); C07K 16/2887 (2013.01); C07K 16/2896 (2013.01); C12N 9/003 (2013.01); C12N 15/63 (2013.01); C12N 15/86 (2013.01); C12Y 105/01003 (2013.01); G01N 33/6803 (2013.01); C07K 2317/622 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/20 (2013.01); C07K 2319/35 (2013.01); C07K 2319/81 (2013.01); C07K 2319/95 (2013.01); C12N 2740/15043 (2013.01);
Abstract

The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest.

Find Patent Forward Citations

Bradner, James. (2024). Compositions and methods for selective protein degradation (U.S. Patent No. 11999802). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11999802

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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