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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11999757 B1

PDFFull Text
Date of Patent:
Jun. 04, 2024

Filed:

Oct. 30, 2018

Synthesis of boronate ester derivatives and uses thereof

Applicant:

Melinta Subsidiary Corp., Parsippany, NJ (US);

Inventors:

Serge Henri Boyer, San Diego, CA (US);

Scott J. Hecker, Del Mar, CA (US);

Gerardus K. M. Verzijl, Well, NL;

Petrus J. Hermsen, Horst, NL;

Assignee:

MELINTA SUBSIDIARY CORP., Parsippany, NJ (US);

Attorney:

Wilmer Cutler Pickering Hale and Dorr LLP

Primary Examiner:

Yevgeny Valenrod

Assistant Examiner:

Blaine G Doletski

Int. Cl.
CPC ...
C07F 5/02 (2006.01); B01J 23/46 (2006.01); C07C 67/31 (2006.01); C07C 69/675 (2006.01); C07F 5/04 (2006.01); C12P 9/00 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); B01J 23/462 (2013.01); C07C 67/31 (2013.01); C07C 69/675 (2013.01); C07F 5/04 (2013.01); C12P 9/00 (2013.01);
Abstract

Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

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Boyer, Serge. (2024). Synthesis of boronate ester derivatives and uses thereof (U.S. Patent No. 11999757). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11999757

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