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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11999716 B1

PDFFull Text
Date of Patent:
Jun. 04, 2024

Filed:

Oct. 24, 2019

Wdr5 inhibitors and modulators

Applicant:

Vanderbilt University, Nashville, TN (US);

Inventors:

Taekyu Lee, Brentwood, TN (US);

Joseph R. Alvarado, Cleveland Heights, OH (US);

Jianhua Tian, Nashville, TN (US);

Kenneth M. Meyers, Nashville, TN (US);

Changho Han, Nashville, TN (US);

Jonathan J. Mills, Nashville, TN (US);

Kevin B. Teuscher, Nashville, TN (US);

Shaun R. Stauffer, Brentwood, TN (US);

Stephen W. Fesik, Nashville, TN (US);

Rocco D. Gogliotti, Kingston Springs, TN (US);

Assignee:

Vanderbilt University, Nashville, TN (US);

Attorney:

Michael Best & Friedrich LLP

Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

Eric Tran

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 217/16 (2006.01); C07D 401/06 (2006.01); C07D 405/14 (2006.01); C07D 413/06 (2006.01); C07D 413/14 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 217/16 (2013.01); C07D 401/06 (2013.01); C07D 405/14 (2013.01); C07D 413/06 (2013.01); C07D 413/14 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01);
Abstract

Isoquinolinone compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.

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Lee, Taekyu. (2024). Wdr5 inhibitors and modulators (U.S. Patent No. 11999716). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11999716

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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