The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2024
Filed:
Nov. 26, 2019
Applicant:
Duke University, Durham, NC (US);
Inventors:
Tarun Saxena, Durham, NC (US);
Ravi Bellamkonda, Durham, NC (US);
Nassir Mokarram-Dorri, Atlanta, GA (US);
Assignee:
DUKE UNIVERSITY, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/65 (2017.01); B82Y 5/00 (2011.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6929 (2017.08); A61K 47/65 (2017.08); C07K 14/705 (2013.01); B82Y 5/00 (2013.01);
Abstract
Compositions are provided, the compositions comprising: (1) a nanoparticle; (2) optionally, a linker and/or masking agent; and (3) a ligand configured to activate peri-tumoral cells to induce scarring by the peri-tumoral cells. In some aspects, administration of the compositions to a subject may generate an environment capable of walling-off and containing invasive tumors.