The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2024
Filed:
Jun. 04, 2021
Development Center for Biotechnology, Taipei, TW;
Shih-Hsien Chuang, Taipei, TW;
Wei-Ting Sun, Taipei, TW;
Ying-Shuan Lailee, Taipei, TW;
Chun-Liang Lai, Taipei, TW;
Wun-Huei Lin, Taipei, TW;
Win-Yin Wei, Taipei, TW;
Shih-Chong Tsai, Taipei, TW;
Cheng-Chou Yu, Taipei, TW;
Chao-Yang Huang, Taipei, TW;
DEVELOPMENT CENTER FOR BIOTECHNOLOGY, Taipei, TW;
Abstract
The present disclosure provides an immunoconjugate includes an antibody comprising an antigen-binding fragment that specifically binds to an epitope in mesothelin, N-glycan binding domain and an N-glycan; a linker linking to the N-glycan; and a payload A and a payload B conjugated to the linker, respectively; wherein the payload A and the payload B are the same or different. A pharmaceutical composition comprises the immunoconjugate and a method for treating cancer are also provided in the disclosure.