The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2024
Filed:
Jan. 31, 2019
Applicant:
Akamis Bio Limited, Oxfordshire, GB;
Inventors:
Simon Alvis, Oxfordshire, GB;
Magdalena Kieltyka, Oxfordshire, GB;
Assignee:
AKAMIS BIO LIMITED, Oxfordshire, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/761 (2015.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 47/10 (2017.01); A61K 47/18 (2017.01); A61K 47/20 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 47/10 (2013.01); A61K 47/183 (2013.01); A61K 47/20 (2013.01); A61K 47/26 (2013.01);
Abstract
The present disclosure provides a liquid formulation suitable for a group B adenovirus, comprising: a) a group B adenovirus, such as replication competent group B adenovirus, b) 15 to 25% v/v glycerol, for example 16, 17, 18, 19, 20, 21% v/v glycerol; and c) 0.1 to 1.5% v/v ethanol, for example 0.2-1%, such as 1% v/v ethanol; and d) a buffer, and e) optionally an amino acid, wherein the pH of the formulation is in the range 8.0 to 9.6, and use of the same in treatment, particular in the treatment of cancer.