The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2024
Filed:
Jan. 03, 2017
Applicant:
Glaxosmithkline Biologicals SA, Rixensart, BE;
Inventors:
Christiane Marie-Paule Simone Jeanne Feron, Rixensart, BE;
Sandra Giannini, Rixensart, BE;
Assignee:
GLAXOSMITHKLINE BIOLOGICALS SA, Rixensart, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/04 (2006.01); A61K 35/76 (2015.01); A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 48/00 (2006.01); A61P 31/04 (2006.01); C12N 9/24 (2006.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01); C40B 40/02 (2006.01);
U.S. Cl.
CPC ...
A61K 35/76 (2013.01); A61K 39/00 (2013.01); A61K 39/02 (2013.01); A61K 48/0008 (2013.01); A61K 48/005 (2013.01); A61P 31/04 (2018.01); C12N 9/2405 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); C12Y 302/01087 (2013.01); A61K 2039/5256 (2013.01); C12N 2795/00032 (2013.01); C12N 2795/00034 (2013.01); C12N 2795/00043 (2013.01); C12N 2800/24 (2013.01); C12N 2830/00 (2013.01); C40B 40/02 (2013.01); Y02A 50/30 (2018.01);
Abstract
The present invention discloses a recombinant bacteriophage comprising a phage genome polynucleotide including a gene encoding a heterologous antigen protein(s) and a killing gene encoding a protein that is capable of killing a host bacterium. Such a recombinant bacteriophage is designed to prime a subject's immune response and to kill the bacterium that it infects such that the 'prime and kill' bacteriophage provides two lines of protection against infectious disease.