The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2024

Filed:

May. 17, 2019
Applicants:

Industry-academic Cooperation Foundation, Yonsei University, Seoul, KR;

National Cancer Center, Goyang-si, KR;

Inventors:

Seok-Gu Kang, Suwon-si, KR;

Soo Youl Kim, Goyang-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); A61K 31/11 (2006.01); A61K 31/155 (2006.01); A61K 45/06 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/495 (2013.01); A61K 31/11 (2013.01); A61K 31/155 (2013.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01);
Abstract

The present disclosure relates to a pharmaceutical composition for treating brain cancer containing an aldehyde inhibitor and an anticancer drug. Since there are many types of brain cancer and the boundary between brain cells and tumor cells in brain cancer is not clear, brain cancer is particularly difficult to treat. The pharmaceutical composition of the present disclosure may further contain a biguanide-based compound as needed, wherein the compound is preferably phenformin. The pharmaceutical composition of the present disclosure is very effective for the treatment and improvement of prognosis of brain cancer, and has remarkable effects of killing cancer cells and inhibiting cancer stem cell characteristics, compared to when each of the active ingredients is administered alone. Thus, it is expected that the pharmaceutical composition of the present disclosure will be widely used in the field of brain cancer treatment.


Find Patent Forward Citations

Loading…