The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2024

Filed:

Mar. 06, 2023
Applicant:

Janssen Pharmaceuticals, Inc., Titusville, NJ (US);

Inventors:

Philippe Fernandes, Beerse, BE;

Mark Schmidt, Antwerp, BE;

Vanina Popova, Nijlen, BE;

Adam Savitz, Greenwich, CT (US);

Rama Melkote, Basking Ridge, NJ (US);

Wayne C. Drevets, Rancho Santa Fe, CA (US);

Srihari Gopal, Belle Mead, NJ (US);

Darrel Pemberton, Oud Turnhout, BE;

Chakradhar Lagishetty, King of Prussia, PA (US);

Iva Kezic, Antwerp, BE;

Assignee:

Janssen Pharmaceuticals, Inc., Titusville, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61P 25/24 (2006.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61P 25/24 (2018.01); C07B 2200/13 (2013.01);
Abstract

The disclosure provides crystalline and amorphous forms of aticaprant. Also provided by the disclosure are pharmaceutical compositions comprising the amorphous or crystalline forms, methods of treating major depressive disorder using the amorphous or crystalline forms of aticaprant, amorphous or crystalline forms of aticaprant for use in the treatment of major depressive disorder in a human patient having anhedonia, uses of the amorphous or crystalline forms of aticaprant in the manufacture of a medicament for the treatment of major depressive disorder, and packages or pharmaceutical products comprising (i) amorphous or crystalline forms of aticaprant and (ii) instructions for treating major depressive disorder. In some aspects, the human patient treated as described herein has anhedonia.


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