The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2024
Filed:
Apr. 07, 2021
Abbott Laboratories, Abbott Park, IL (US);
Cedars-sinai Medical Center, Los Angeles, CA (US);
Jennifer Van Eyk, Los Angeles, CA (US);
Beth McQuiston, Abbott Park, IL (US);
Saul Datwyler, Abbott Park, IL (US);
Raj Chandran, Abbott Park, IL (US);
Vidya Venkatraman, Los Angeles, CA (US);
Shenyan Zhang, Los Angeles, CA (US);
ABBOTT LABORATORIES, Abbott Park, IL (US);
CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US);
Abstract
The present disclosure relates to methods for diagnosing and evaluating a subject that has sustained or may have sustained an injury to the head, such as a traumatic brain injury (TBI). In particular, the present disclosure identifies various biomarkers, the detection and/or differential expression of which can be used to assess the presence or absence of a TBI in a subject, and can be used as a basis for diagnosing a subject as having a specific type of TBI (e.g., severe TBI or subclasses of mild TBI). The various TBI biomarkers can be detected individually or in combination and can be used as an important diagnostic, prognostic, and/or TBI risk stratification tool as part of assessing a subject's TBI status.