The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2024

Filed:

Jun. 22, 2018
Applicant:

Nanotemper Technologies Gmbh, Munich, DE;

Inventors:

Philipp Baaske, Munich, DE;

Stefan Duhr, Munich, DE;

Dennis Breitsprecher, Munich, DE;

Christian Osseforth, Munich, DE;

Axel Rohde, Munich, DE;

Amin Jean Gupta, Munich, DE;

Nuska Tschammer, Munich, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/58 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/582 (2013.01); G01N 33/54313 (2013.01);
Abstract

A method for measuring interactions between labeled particles and ligands comprising the steps: a) providing a sample comprising labeled particles and ligands in a solution, wherein the labeled particles are dissolved or dispersed in the solution or are immobilized on a solid support; b) exciting fluorescently the labeled particles and detecting the fluorescence of the excited particles at a predetermined temperature; c) repeating steps (a) and (b) multiple times at different concentrations of the ligands in the solution; and d) determining the interaction between the labeled particles and the ligands based on the ligand concentration dependent change of the fluorescence of the labeled particles, wherein the labeled particles are labeled with one or more dyes.


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