The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2024

Filed:

Jun. 07, 2021
Applicant:

Snapdragon Chemistry, Inc., Waltham, MA (US);

Inventors:

Adrian G. Amador, Framingham, MA (US);

Yuanqing Fang, Belmont, MA (US);

David D. Ford, Cambridge, MA (US);

Mikhail V. Goncharuk, West Roxbury, MA (US);

Grace Russell, Waltham, MA (US);

Assignee:

Snapdragon Chemistry, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/30 (2006.01); G01N 30/02 (2006.01); G01N 30/32 (2006.01); G01N 30/84 (2006.01); G01N 30/88 (2006.01);
U.S. Cl.
CPC ...
G01N 30/88 (2013.01); G01N 30/30 (2013.01); G01N 30/32 (2013.01); G01N 30/84 (2013.01); G01N 2030/027 (2013.01); G01N 2030/324 (2013.01); G01N 2030/8435 (2013.01); G01N 2030/8804 (2013.01); G01N 2030/8809 (2013.01);
Abstract

The present disclosure relates to a computer-implemented method for analyzing a product stream of a chemical reaction. The method includes withdrawing a portion of the product stream of the chemical reaction from a reactor, the portion of the product stream having a volume of less than about 200 μL. The method further includes mixing the portion of the product stream with a diluent to produce a sample and then transferring the sample to a liquid chromatography device. A measured chemical profile is then developed, via the liquid chromatography device, which can be used for process monitoring or real time decision making. In some embodiments, the method can include adjusting a reaction condition in the reactor based on differences between the measured chemical profile and a desired chemical profile.


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