The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2024

Filed:

Feb. 25, 2020
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Matthew A. Lauber, North Smithfield, RI (US);

Martin Gilar, Franklin, MA (US);

Mathew H. DeLano, Needham, MA (US);

Michael Donegan, Charlton, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/26 (2006.01); B01D 15/18 (2006.01); B01D 15/22 (2006.01); B01D 15/36 (2006.01); B01D 15/38 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
G01N 30/26 (2013.01); B01D 15/1878 (2013.01); B01D 15/22 (2013.01); B01D 15/361 (2013.01); B01D 15/3847 (2013.01); G01N 2030/027 (2013.01);
Abstract

The present disclosure relates to the determination of analytes in a sample using chromatography. The present disclosure provides methods of separating an analyte from a sample. The method includes introducing a sample comprising the analytes into a chromatographic system. The chromatographic system has a flow path disposed in an interior of the chromatographic system, at least a portion of the flow path having an active coating, and a chromatographic column having a stationary phase material in an interior of the chromatographic column that facilitates separation of the analytes in the sample through interaction with at least one analyte in the sample. The active coating is selected to interact with at least one analyte in the sample through (1) a repulsive force, (2) a secondary interaction, or (3) a retention mechanism distinct from the interaction with the stationary phase material.


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