The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2024

Filed:

Jan. 10, 2018
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Omar Khaled Ahmad, Providence, RI (US);

Stephen Paul Brown, Mystic, CT (US);

Kenneth John Dirico, Gales Ferry, CT (US);

Russell Dushin, Old Lyme, CT (US);

Gary Frederick Filzen, Schwenksville, PA (US);

Sujiet Puthenveetil, Franklin, MA (US);

Pavel Strop, San Mateo, CA (US);

Chakrapani Subramanyam, South Glastonbury, CT (US);

Lawrence N. Tumey, Pawcatuck, CT (US);

Assignee:

Pfizer, Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/26 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07H 15/26 (2013.01); A61K 47/6807 (2017.08); A61P 35/00 (2018.01); A61K 45/06 (2013.01);
Abstract

The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC's), and to payload-linker compounds and ADC compounds comprising the same; to pharmaceutical compositions comprising the same and to methods for using the same to treat pathological conditions such as cancer.


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