The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2024
Filed:
Jul. 16, 2021
Janssen Pharmaceutica NV, Beerse, BE;
Tongfei Wu, Boortmeerbeek, BE;
Dirk Brehmer, Freiburg, DE;
Lijs Beke, Antwerp, BE;
An Boeckx, Herentals, BE;
Gaston Stanislas Marcella Diels, Turnhout, BE;
Edward Charles Lawson, Pipersville, PA (US);
Lieven Meerpoel, Beerse, BE;
Vineet Pande, Vosselaar, BE;
Marcus Cornelius Bernardus Catharina Parade, Eindhoven, NL;
Wim Bert Griet Schepens, Sint Katelijne Waver, BE;
Weimei Sun, Lower Gwynedd, PA (US);
Johannes Wilhelmus John F. Thuring, Antwerp, BE;
Marcel Viellevoye, Breda, NL;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention relates to novel monocyclic and bicyclic ring system substituted carbanucleoside analogues of Formula (I), wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PRMT5 inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.