The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2024
Filed:
Mar. 14, 2021
Applicant:
Wigen Biomedicine Technology (Shanghai) Co., Ltd., Shanghai, CN;
Inventors:
Assignee:
WIGEN BIOMEDICINE TECHNOLOGY (SHANGHAI) CO., LTD., Shanghai, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/06 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 407/14 (2006.01); C07D 417/14 (2006.01); C07D 491/08 (2006.01); C07D 491/10 (2006.01); C07D 491/107 (2006.01); C07D 498/08 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/06 (2013.01); C07D 519/00 (2013.01);
Abstract
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, a preparation method and application thereof. The compounds can selectively inhibit the activity of epidermal growth factor receptor (EGFR) mutants, and shows good inhibitory effect towards mutant EGFR and anti-proliferative activity against cancer cells. Thus they can be used for treating tumors and related diseases.