The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2024

Filed:

Jun. 21, 2021
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Kevin D. Wyndham, Upton, MA (US);

Michael F. Morris, Ashland, MA (US);

Darryl W. Brousmiche, Grafton, MA (US);

Jason F. Hill, Milford, MA (US);

Jacob N. Fairchild, Upton, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01J 20/28 (2006.01); B01D 15/26 (2006.01); B01D 15/30 (2006.01); B01D 15/32 (2006.01); B01D 15/40 (2006.01); B01D 53/02 (2006.01); B01J 20/22 (2006.01); B01J 20/283 (2006.01); B01J 20/288 (2006.01); B01J 20/289 (2006.01); B01J 20/30 (2006.01); B01J 20/32 (2006.01); C07F 7/18 (2006.01); B01J 20/282 (2006.01); B01J 20/284 (2006.01); B01J 20/285 (2006.01);
U.S. Cl.
CPC ...
B01J 20/283 (2013.01); B01D 15/26 (2013.01); B01D 15/30 (2013.01); B01D 15/305 (2013.01); B01D 15/322 (2013.01); B01D 15/40 (2013.01); B01D 53/025 (2013.01); B01J 20/22 (2013.01); B01J 20/28004 (2013.01); B01J 20/28016 (2013.01); B01J 20/28042 (2013.01); B01J 20/28057 (2013.01); B01J 20/28059 (2013.01); B01J 20/28061 (2013.01); B01J 20/28064 (2013.01); B01J 20/28066 (2013.01); B01J 20/28069 (2013.01); B01J 20/28071 (2013.01); B01J 20/28073 (2013.01); B01J 20/28076 (2013.01); B01J 20/28078 (2013.01); B01J 20/28083 (2013.01); B01J 20/28085 (2013.01); B01J 20/288 (2013.01); B01J 20/289 (2013.01); B01J 20/3085 (2013.01); B01J 20/3204 (2013.01); B01J 20/3206 (2013.01); B01J 20/3208 (2013.01); B01J 20/3246 (2013.01); B01J 20/3285 (2013.01); B01J 20/3293 (2013.01); C07F 7/1804 (2013.01); B01J 20/282 (2013.01); B01J 20/284 (2013.01); B01J 20/285 (2013.01); B01J 20/32 (2013.01); B01J 20/3234 (2013.01); B01J 2220/54 (2013.01); B01J 2220/80 (2013.01);
Abstract

In one aspect, the present invention provides a chromatographic stationary phase material for various different modes of chromatography represented by Formula 1: [X](W)(Q)(T)(Formula 1). X can be a high purity chromatographic core composition having a surface comprising a silica core material, metal oxide core material, an inorganic-organic hybrid material or a group of block copolymers thereof. W can be absent and/or can include hydrogen and/or can include a hydroxyl on the surface of X. Q can be a functional group that minimizes retention variation over time (drift) under chromatographic conditions utilizing low water concentrations. T can include one or more hydrophilic, polar, ionizable, and/or charged functional groups that chromatographically interact with the analyte. Additionally, b and c can be positive numbers, with the ratio 0.05≤(b/c)≤100, and a≥0.


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